منابع مشابه
Selection of antitumor displayed peptides for the specific delivery of the anticancer drug lactaptin
It has been previously demonstrated that lactaptin, the proteolytic fragment of human milk protein κ-casein, induces the death of various cultured cancer cells. The recombinant analog of lactaptin, RL2, effectively induces the apoptosis of mouse hepatocarcinoma-1 (HA-1) tumor cells in vitro and suppress the growth of HA-1 tumors and metastases in vivo. The antitumor drug Lactaptin developed on ...
متن کاملTumor-Specific Peptide, Selected from a Phage Peptide Library, Enhances Antitumor Activity of Lactaptin
A recombinant analogue of lactaptin (RL2), a new potential anticancer molecule, induces apoptosis in cultured tumor cells. The tumor suppression efficacy of RL2 was shown against mouse hepatoma-1 cells and MDA-MB-231 human breast adenocarcinoma cells. The RL2-based therapeutic drug lactaptin is distributed evenly throughout the organism, which reduces its antitumor efficacy. In the current stud...
متن کاملTest for Potential Antitumor Agents1
HEINEMANN, BERNARD (Bristol Laboratories, Syracuse, N.Y.), AND ALMA J. HOWARD. Induction of lambda-bacteriophage in Escherichia coli as a screening test for potential antitumor agents. Appl. Microbiol. 12:234-239. 1964.A simple, rapid, quantitative test procedure to measure induction of phage production in lysogenic Escherichia coli K-12 (X) was described. This test was used in a study of 209 s...
متن کاملAntibacterial and antitumor potential of actinomycetes isolated from mangrove soil in the Maowei Sea of the southern coast of China
Mangroves are the tidal forest existing in the intertidal zone and usually considered as the special marine ecosystem. In the present study, 452 actinomycetes were recovered from nine diferent sites at Maowei Sea Mangrove Reserve in Qinzhou (Guangxi province, China). Among them, Seventy-four strains were purified for 16s RNA gene sequencing and further characterization. The results indicated th...
متن کاملAntibacterial and antitumor potential of actinomycetes isolated from mangrove soil in the Maowei Sea of the southern coast of China
Mangroves are the tidal forest existing in the intertidal zone and usually considered as the special marine ecosystem. In the present study, 452 actinomycetes were recovered from nine diferent sites at Maowei Sea Mangrove Reserve in Qinzhou (Guangxi province, China). Among them, Seventy-four strains were purified for 16s RNA gene sequencing and further characterization. The results indicated th...
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ژورنال
عنوان ژورنال: Biology and Medicine
سال: 2015
ISSN: 0974-8369
DOI: 10.4172/0974-8369.1000s2-004